Composition: 1 tablet contains: active ingredients: selenium (in the form of selenomethionine) - 100 μg (μg), which corresponds to 181.2%*, iodine (in the form of potassium iodide) - 150 μg (μg), which corresponds to 100.0% *; auxiliary substances: microcrystalline cellulose, lactose monohydrate, potato starch, calcium stearate, Aerosil; the shell of the tablet is white (in the composition: sugar, prepared water, magnesium carbonate, aerosol, polyvinylpyrrolidone, titanium oxide, beeswax).
* – percentage of the daily need for minerals for adults.
The functional properties of "TIRBISODtm" are determined by the physiological activity of the substances included in its composition.
Iodine is a trace element necessary for the body, which must be supplied regularly with food. Its only clearly established function is the production of an important element in the synthesis of thyroid hormones. Iodine, which enters the body in physiological quantities, prevents the development of endemic goiter associated with a lack of this element in food; normalizes the size of the thyroid gland in newborns, children and young adult patients; affects the indicators of the T3/T4 ratio, the level of thyroid-stimulating hormone (TSH).
The recommended daily allowance of iodine for adults and children 12 years of age and older with thyroid disease is 150 micrograms (mcg).
Selenium is an important trace element that plays an important role in the functioning of the thyroid gland. Data from the literature indicate that selenium intake by patients with autoimmune thyroiditis is associated with a decrease in the level of antibodies to anti-thyroperoxidase, improvement in ultrasound parameters of the thyroid gland, and an increase in quality of life. In adults, the thyroid gland has the highest concentration of selenium in the body.
Selenium deficiency is associated with various thyroid disorders, including hypothyroidism, subclinical hypothyroidism, Hashimoto's autoimmune thyroiditis, thyroid enlargement (goiter), thyroid tumors, and Graves' disease.
A randomized, double-blind, placebo-controlled trial compared the effects of 100 mcg/day of selenium, 1200 mg/day of pentoxifylline (an anti-inflammatory) or placebo for 6 months in 159 patients with mild Graves' orbitopathy (endocrine exophthalmos). Compared to other patients, those receiving selenium reported a higher quality of life. In addition, ophthalmic outcomes improved in 61% of patients in the selenium group compared to 36% in the placebo group. And only 7% of patients in the selenium group had mild disease progression compared to 26% in the placebo group.
Selenium is available in the form of selenomethionine or selenium-enriched yeast, as well as selenite. The human body absorbs more than 90% of selenomethionine, and only about 50% of selenium from selenite.**
Maintaining a balance between iodine and selenium is critical for normal thyroid function and prevention of autoimmune thyroid disease. Selenium also helps protect the thyroid gland from oxidative damage caused by excess iodine during hormone synthesis.
It is important to note that the effect of iodine and selenium supplementation on thyroid hormone levels may vary depending on individual factors such as baseline nutrient levels and overall thyroid health. It is recommended to consult a doctor before taking any dietary supplements.
** - Wiley Online Library "Clinical Endocrinology" https://onlinelibrary.wiley.com/doi/full/10.1111/cen.12066
Recommendations for use: as a dietary supplement to the diet as an additional source of iodine and selenium. It has a beneficial effect on the state of the thyroid gland and can be used to prevent conditions associated with iodine and selenium deficiency, as well as to enrich the diet of residents of regions with a limited supply of iodine from the environment.
Use during the period of complex therapy of diseases of the thyroid gland only after consultation with a doctor.
It is not a medicine.
Method of use and recommended daily dose: children over 12 years of age and adults should take 1 tablet 1 time a day during or after meals, washed down with a sufficient amount of drinking water. A doctor's consultation is recommended before use.
Term of use: determined by the doctor individually. The preventive course of consumption is usually 6-12 months. Further use and the possibility of a repeat course are recommended to be agreed with the doctor.
Precautions for use: do not exceed the recommended daily amount (dose). The dietary supplement should not be used as a substitute for a complete diet.
Contraindications for use: pronounced hyperthyroidism, pulmonary tuberculosis, hemorrhagic diathesis, Düring's herpetiform dermatitis, increased individual sensitivity to any of the components.
Release form: tablets weighing 200 mg (mg) ± 10.0% No. 25 in a blister packed in a cardboard box.
Storage conditions: store in the original packaging at a temperature not higher than 25 °С in the village
