Composition: 1 capsule contains: active ingredients:

• saccharomyces boulardi Lynside® Pro SCB (Saccharomyces boulardii CNCM I-3799) - 250 mg (mg) [containing 2.0x1010 CFU (CFU) in 1 g (g)*],
• zinc (in the form of zinc gluconate) - 10.0 mg (mg), which corresponds to 68.0%*;
• excipients: filler: maltodextrin; capsule shell: gelatin or capsule shell: gelatin, dye: titanium dioxide, or capsule shell: gelatin, dye: zinc oxide.

CFU = colony-forming unit.

* – percentage of the daily need for minerals.

The functional properties of the dietary supplement "Esbularditm" are determined by the components included in its composition.

Saccharomyces boulardii CNCM I-3799 have a direct antimicrobial effect, and the mechanism of action of Saccharomyces boulardii is related to their ability to inhibit the growth of pathogenic and opportunistic microorganisms and fungi, such as Clostridium difficile, Clostridium pneumoniae, Staphulococcus aureus, Pseudomonas aeruginosa, Candida krusei , Candida pseudotropical, Candida albicans, Salmonella typhi, Salmonella enteritidis, Escherichia coli, Shigella dysenteriae, Shigella flexneri, Klebsiella, Proteus, Vibrio cholerae, as well as Entamoeba hystolitica, Lambliae; Enterovirus, Rotavirus.

Saccharomyces boulardii is included in the treatment protocol of Management of Helicobacter pylori infection.

Among the main mechanisms of action of CNCM I-3799 is the production of proteases that break down bacterial toxins and affect the receptors of the small intestinal epithelium to which the toxins can bind. CNCM I-3799 also reduces the secretion of water and electrolytes into the intestinal lumen (which is especially important for reducing the intensity of diarrhea). This is achieved by reducing the production of cyclic adenosine monophosphate in the cells of the small intestinal epithelium.

The natural resistance of CNCM I-3799 strains to the action of antibiotics allows them to be used simultaneously with antibiotics.

In addition, the ability of CNCM I-3799 to strengthen the immune defense of mucous membranes by increasing the production of IgA and secretory components of other immunoglobulins was established.

Saccharomyces boulardii is included in the protocol for the treatment of diseases caused by Helicobacter pylori infection according to the Maastricht Consensus 6 revision (2022).

Zinc is a key mineral that cells use to metabolize nutrients. It has anti-inflammatory, wound-healing, antioxidant and antibacterial effects, and is also responsible for transporting water and electrolytes in the intestine. It is known from clinical studies that zinc has a beneficial effect on the clinical course of acute diarrhea, reducing both its severity and its duration. The absorption of zinc differs significantly from its form, so the absorption of zinc gluconate reaches 60.9% and is one of the most effective forms of zinc before consumption. In addition, zinc gluconate is included in WHO recommendations for the treatment and prevention of diarrhea.

Recommendations for use: as a dietary supplement to the diet, as an additional source of biologically active substances that favorably affect the functional state of the intestine in order to normalize the intestinal microflora after taking antibiotics, as well as to normalize the work of the large intestine in case of its functional disorders and travelers' diarrhea .

It is not a medicine.

Method of use and recommended daily dose: take 1-2 capsules 1-2 times a day for children over 12 years old and adults. Capsules should be swallowed without chewing, with a sufficient amount of drinking water. Do not mix with very hot (over 50 °C) or cold drinks, food, liquids containing alcohol. A doctor's consultation is recommended before use.

Term of use: 10–14 days.

The maximum term of use is 30 days.

Precautions for use: do not exceed the recommended daily dose. The dietary supplement should not be used as a substitute for a complete diet.

Contraindications for use: pregnancy, lactation period, children under 12 years and increased individual sensitivity to any of the components.

Storage conditions: store in the original packaging at a temperature not higher than 25 °C in a dry place protected from direct sunlight and out of the reach of children.