1 Voger capsule contains:
- saw Palmetto fruit extract (Serenoa repens) - 160 mg (mg),
- pumpkin seed extract (Cucurbita moschata) - 60 mg (mg),
- african potato tuber extract (Hypoxis hemerocallidea) - 50 mg (mg),
- stinging nettle root extract (Urtica dioica) - 50 mg (mg),
- african plum bark extract (Prunus africana) - 40 mg (mg),
- rye pollen extract (Secale cereale) - 25 mg (mg);
Functional properties:
In the etiology of pathological processes that lead to impaired urination in men, pain and sexual dysfunction, an important role is played by an increase in the production of the androgen dihydrotestosterone (DHT), which causes the growth of prostate tissue by binding to cytoplasmic androgen receptors. DHT is formed from testosterone by activation of the enzyme 5-α-reductase. And also, activation of α-adrenoceptors, which increase the concentration of calcium ions inside the cell, and leads to the contraction of smooth muscles.
The functional properties of the dietary supplement "Voger" are due to the physiological activity of biologically active substances included in its composition: fatty acids (lauric, myristic, oleic, palmitic, stearic, linoleic) and phytosterols (ß-sitosterol, campesterol, stigmasterol), curbitin and fatty oil, zinc, hypoxoside, aglycon and rooperol, vitamins (K, C, B2, B3, carotenoids), chlorophyll, tannins, organic acids, flavonoids, macro- and microelements (Si, Fe, Ca, Cu, K, Mn, B, Ti, Ni), pentacyclic triterpenes, n-docosanol and tetracosanol.
Biologically active substances included in Voger have anti-inflammatory, anti-androgenic and anti-estrogenic properties. They are able to reduce the level of globulin, which binds sex hormones. The most important components of phytotherapy are phytosterols, ß-sitosterol, fatty acids and lectins. These substances inhibit aromatase, lipoxygenase and growth factor, which stimulate the proliferation of prostate cells. Including suppress α-adrenoreceptors, 5-α-reductase, muscarinic cholinergic receptors, dihydropyridine receptors or vanilloid receptors and neutralize free radicals.
The biologically active substances included in Voger reduce the pathological processes of the prostate gland, which are accompanied by frequent urges to urinate, especially at night, weak or intermittent urination, the feeling of an incompletely emptied bladder, discomfort, including during urination, uncomfortable sensations in the lower abdomen or in the perineum, and sexual dysfunction.
"Voger" includes all the components listed in the "Phytotherapy" section of the 2019 Recommendations for the treatment of benign prostatic hyperplasia of the European Association of Urologists:
Saw Palmetto fruit extract (Serenoa repens) contains 45% fatty acids (lauric, myristic, oleic, palmitic, stearic, linoleic) and phytosterols (β-sitosterol, campesterol, stigmasterol).
Saw palmetto improves urinary symptom scores, IPSS symptoms, and urinary flow scores. Contributes to the blocking of 5-α-reductase and suppression of the binding of dehydrotestosterone to prostate receptors. The antiproliferative effect is due to inhibition of the activity of 5-α-reductase and aromatase enzymes.
Saw palmetto extract is one of the leaders among herbal remedies that suppress the development of edema, inflammation in the prostate and reduce the size of the prostate gland. Numerous clinical studies of Saw Palmetto extract in Germany, England, USA and other countries have shown its high effectiveness in chronic prostatitis. The absence of undesirable effects allows the use of Saw Palmetto extract for a long time, without fear of harmful consequences for the body. In addition, Saw Palmetto extract has a beneficial effect on the condition of the skin and hair by blocking 5-α-reductase type 2, which is a key link in the development of androgenic alopecia (hair loss) and acne.
Saw palmetto fruit extract leads to a reduction in the size of the prostate gland and an improvement in symptoms. Helps to stop the conversion of testosterone into dihydrotestosterone, that is, to eliminate the leading cause of the development of benign prostatic hyperplasia (BPH).
Pumpkin seed extract (Cucurbita pepo) contains the amino compound cucurbitin and fatty oils that have anti-inflammatory, restorative, antioxidant, immunomodulatory, regenerative and antiparasitic properties.
The consumption of pumpkin products is accompanied by a decrease in the volume of the prostate gland, through anti-inflammatory and antiandrogenic effects, a decrease in detrusor activity, an improvement in the International Prostate Symptom Scale (IPSS), parameters of uroflowmetry and quality of life (QoL).
Pumpkin seeds are also a powerful source of zinc, which plays an important role in the functioning of the genitourinary system in men, helps to strengthen sexual function and normalize the functional state of the prostate gland in case of prostatitis and adenoma.
African potato tuber extract (Hypoxis hemerocallidea) enhances the action of Saw Palmetto. The rhizome of the African potato plant (Hypoxis hemerocallidea) is known for its traditional use in the treatment of BAH and other genitourinary disorders, including bladder infections.
The extract obtained from the African potato tuber has the main bioactive compound hypoxoside, aglycone and rooperol and provides the strongest evidence of efficacy and safety in normalizing the functional state in BAH.
Root extract contains (Urtica dioica) a complex of biologically active compounds, including vitamins (K, C, B2, B3, carotenoids), chlorophyll, tannins, organic acids, flavonoids, macro- and microelements (Si, Fe, Ca, Cu, K, Mn, B, Ti, Ni).
It helps to increase the level of hemoglobin, reduce the level of glucose in the blood, normalize lipid metabolism and increase the general tone of the body. Stinging nettle root extract helps reduce swelling and prevents the process of prostate enlargement.
African plum (Prunus africana) bark extract contains a number of biologically active substances (phytosterols, pentacyclic triterpenes, n-docosanol and tetracosanol), which have anti-inflammatory and anti-edematous properties, due to inhibition of prostaglandin production, reduction of prolactin levels in the prostate gland.
Based on preclinical studies, several mechanisms of action have been proposed, including inhibition of 5-α-reductase, α-adrenergic antagonism, inhibition of dihydrotestosterone and receptors, which contributes to the reduction of prostate tissue proliferation.
Rye pollen (Secale cereale) has a number of effects, including urethral and bladder relaxation, and smooth muscle relaxation through α-adrenergic receptor antagonism.
Additional mechanisms include induction of apoptosis in prostate epithelial cells and inhibition of prostaglandin and leukotriene biosynthesis.
Through its anti-inflammatory effect, rye pollen reduces the size of the prostate gland in BPH, prostatitis and prostatodynia, improving symptoms such as nocturia and frequent urination.
The product does not contain gluten, GMO and soy.
Recommendations for use: it is recommended to be taken in the diet as an additional source of biologically active substances and fatty acids, in order to normalize the functional state of the urinary system of men, with symptoms of the lower urinary tract, with discomfort during intercourse, including with benign prostatic hyperplasia and chronic prostatitis.
The package contains 30 capsules, which is enough for 15 days of intake.
Method of use and recommended daily dose: adult men take 1 capsule 2 times a day after meals. A doctor's consultation is recommended before use.
Features of use: regular daily consumption is especially important for the normalization of the functional state of the prostate gland. The effectiveness of the components in relation to the symptoms of the lower urinary tract is manifested 2-3 weeks after the start of use. Full effectiveness can be achieved no earlier than after 3 months. It is recommended to use a complete and balanced diet, to limit animal fats, sugar, sweets and alcohol.
Precautions for use: do not exceed the recommended daily dose. The dietary supplement should not be used as a substitute for a complete diet.
Contraindications for use: increased individual sensitivity to any of the components.