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Composition: 1 capsule contains: active ingredients: marine magnesium "Simag 55" - 272 mg (mg) (in terms of magnesium - 150 mg (mg), which corresponds to 27.3%*), orotic acid (vitamin B13) - 25 mg (mg), pyridoxine hydrochloride (vit. B6) - 2.7 mg (mg), (corresponding to 112.5%*); excipients: filler: maltodextrin; capsule shell: gelatin, dye: zinc oxide.
* - percentage of the daily requirement of vitamins and minerals for women during pregnancy.
The functional properties of Pregnemag® dietary supplement are determined by the physiological activity of biologically active substances that are part of the active ingredients.
An important role for the normal development of the fetus and the physiological course of pregnancy is played by the full nutrition of the expectant mother. The diet of pregnant women should be balanced in the composition of macro- and micronutrients, taking into account the growing needs for their intake, which as the gestation period increases, it becomes more and more difficult to satisfy only at the expense of food products.
In this regard, the generally accepted tactic of pre-gravid preparation and pregnancy management is nutritional support, which involves the preventive appointment of various vitamin and mineral complexes. The need for their use does not cause doubts among scientists and health care specialists. For example, magnesium is a mineral that is vital for the normal functioning of the human body. During pregnancy, the need for magnesium increases significantly, and the development of its deficiency is not only accompanied by discomfort, but also increases the risk of complications and adverse obstetric and neonatal consequences. Another biologically significant element is B vitamins, which are critically important for the absorption of magnesium, and at the same time necessary for the normal mental development of the future child.
Marine magnesium "Simag 55" produced in France, which is part of Pregnemag®, is a purified natural marine mineral extract. The specific geographical origin allows to obtain a unique mineral profile. A gentle process without solvents allows you to reduce the content of sodium and chlorides in its composition. Magnesium is an essential nutrient and acts as a factor affecting more than 300 enzymes involved in the biological processes of fetal development.
Marine magnesium is an indispensable component of all enzymatic, ATP-dependent reactions; it takes part in the metabolism of carbohydrates, proteins and fats, as well as in redox reactions. Magnesium activates glycolytic enzymes, enzymes of cellular oxidation, enzymes of nucleic acid synthesis; it also plays an important role in the processes of myocardial contraction. Magnesium is a stabilizer of platelets and fibrinogen. The pathogenetic role of magnesium deficiency in hypertension, vasospasm, neoplastic diseases and urolithiasis is generally recognized. Magnesium has a leading role in neuromuscular excitation - in this process it is an antagonist of calcium.
Magnesium is a stabilizer of the processes of mitosis and meiosis, which serves as a key to the formation of a genetically healthy embryo. Among the tissues of the human body, the placenta is characterized by one of the highest levels of magnesium. This is due to the high concentration of mitochondria in it - in fact, it is the center of energy metabolism, which is important for both the fetus and the mother's body.
The daily need for magnesium for women is 280–300 mg (mg), and during pregnancy and lactation it increases by 20–30% to 340–355 mg (mg). The exact necessary dose of the trace element is calculated based on the following indicator: 3.6 mg2 per 1 kg of body weight per day. Some people need more magnesium because of significant losses.
Pyridoxine hydrochloride (vitamin B6), which is part of Pregnemag®, is mainly involved in the metabolism of amino acids, in the form of pyridoxal phosphate, it is part of enzymes that catalyze decarboxylation and transamination, as well as carbohydrates and fats. Promotes the transport of amino acids through the membrane; necessary for activation of phosphorylase, formation of neurotransmitters, gamma-aminobutyric acid, glycine, serotonin. Participates in the exchange of vitamin B12, folic acid, synthesis of porphyrins, unsaturated fatty acids. Activates metabolic processes in the myocardium, especially in hypoxia, can have neurotropic, hematopoietic, cardiotropic and hepatotropic properties. The mechanism of interaction between magnesium and vitamin B6 has not yet been precisely established. The symptoms of deficiency and overdose of both components are similar, however, the symptoms of vitamin B6 deficiency are more pronounced with simultaneous magnesium deficiency, since magnesium is necessary for the activation of pyridoxine-dependent enzymatic systems. Lack of this vitamin is often one of the causes of early toxicosis. For the fetus, vitamin B6 ensures proper development of the brain and nervous system.
Orotic acid (vitamin B13), which is part of Pregnemag®, has a stimulating effect on protein metabolism (on protein synthesis) and growth processes, and has a beneficial effect on the functional state of the liver. The lack of orotic acid leads to a violation of protein metabolism, methionine synthesis, folacin metabolism and pantothenic acid transformations. The ability of orotic acid to stimulate protein synthesis is used in feeding premature babies.
Recommendations for use: it is recommended to be taken in the diet as an additional source of biologically active substances in order to improve the general condition of women with a deficiency of magnesium and vitamins B6 and B13, during pregnancy, as well as as a tonic that has a beneficial effect on the state of the nervous system. It can also be recommended for people with chronic physical and mental fatigue, irritability, increased risk of stress, depression and sleep disorders.
It is not a medicine.
Method of use and recommended daily dose: adults take 1 capsule 2 times a day after meals, capsules should be swallowed without chewing, with a sufficient amount of drinking water.
A doctor's consultation is recommended before use.
The term of use: is determined by the doctor individually, taking into account the nature and features of the degree of vitamin and mineral deficiency, the stability of the achieved effect and receptivity.
Features of use: with simultaneous use of iron preparations, the interval between taking Pregnemag® and these agents should be 2-3 hours. Regular daily intake is especially important during pregnancy or breastfeeding, as the need for magnesium and B vitamins increases significantly during these periods.
Precautions for use: do not exceed the recommended daily dose. The dietary supplement should not be used as a substitute for a complete diet.
Contraindications: increased individual sensitivity to any of the components, children under 12 years of age, glomerulonephritis or pyelonephritis in an acute stage.
Storage conditions: store in the original packaging at a temperature not higher than 25oC in a dry place protected from direct sunlight and inaccessible to children.